I am delighted to read the results of this study, as I have had serious concerns about preservative 282 for several years. I have been interested in the Failsafe diet since I discovered it a year ago through a web search.

My interest is based on two reasons. Firstly, my son developed behaviour problems when he was 2 or 3 years old. Although he was a bright child who did well at school, he would sometimes have uncontrollable rages, often had headaches and felt sick and missed school. At thirteen he became obsessed with drugs, (we lived in a beach suburb which fostered this), refused school, and became sporadically psychotic. Although this was blamed on drugs, I had always known that certain foods might cause his problems. Testing for allergies did not reveal anything conclusive. After eight years of trauma, which caused a deep family rift, during which time there were regular attendances at courts for his uncontrollable behaviour, he became a heavy wine drinker and was accidentally drowned in the sea at the age of 21.

Secondly, I developed a very irritable bowel in my early forties. Trying a rotation diet showed that commercial sliced bread caused severe constipation. Other foods, obtained from the delicatessen, also caused overwhelming sleepiness, headaches and bouts of stomach aches and malaise. It is now so bad that eating any commercial bread or products such as commercial schnitzels, causes an attack which is characterised by bowel cramps, pain, burning sensations in the gut, nausea, headache and muscle spasms in my neck, back and legs. It usually takes three days of fasting, or a rice diet, before the symptoms subside. My medical advisers would never take seriously my claim that bread, cakes and pastries were associated with the problem, although I underwent food challenges under the direction of a respected dietician. Semolina and some home made bread does not cause me any problems. The received view still seems to be that there is a psychiatric component to irritable bowel syndrome, especially as it seems a majority of women are diagnosed with this disorder! Consequently, there is little sympathy for the sufferer, and no treatment other than antispasmodics and anti-flatulence drugs.

I must say that my family and friends still see my disorder as unacceptable, so that I often have to eat things which I know will cause an attack I have been aware of the bicarb antidote for many years, but now find that only a dose of Durolax laxative taken the same day will head off the problem. I want you to know how grateful I feel to you for your persistence in pursuing this research and for publishing the findings so that further research may be undertaken to give your findings scientific credence. - by email, Sydney